ANTIBIOTICS FROM BASIDIOMYCETES XXXIL* STROBILURIN E: A NEW CYTOSTATIC AND ANTIFUNGAL (£)-£-METHOXYACRYLATE ANTIBIOTIC FROM CREPIDO TUS FUL VO TOMENTOSUS PECKá"
نویسندگان
چکیده
The strobilurins, oudemansins and related synthetic mimics constitute a new class of respiration inhibitors which inhibit the electron transfer in the bcx complex. These compounds, both natural and synthetic, contain an (£)-/?-methoxyacrylate (MOA) moiety which is responsible for the antifungal and respiration inhibiting properties2). Strobilurin E was detected and isolated in the course of a screening program for new fungal metabolites capable of reversibly inducing morphological alterations of tumor cells3).
منابع مشابه
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